This research was conducted in the Lath-house of the Department of Horticulture and Landscape Design /College of Agriculture and Forestry/ University of Mosul, to find out the response of Malus domestica Borhk apple transplants of Anna and kagdi varieties to fertilization with Optimus Plus Nano organic fertilizer and ALGACIFO 3000 extract in the vegetative growth of apple transplants, as Optimus Plus Nano fertilizer was sprayed at levels (0, 1.5, 3 mL L^-1) and ALGACIFO 3000 seaweed extract at levels (0, 5, 10 ml L^-1),the results showed a moral superiority of the Anna Variety in the area of one leaf, while the kagdi variety surpassed the number of leaves in its class, as well as the moral effect of fertilization with Optimus plus, especially the coefficient of 3 ml^-1, the highest values were recorded in the character of the number of leaves, the area of the leaves, the leave area and the increase in length and diameter transplants, while the coefficient of 1.5 ml L^-1 Optimus plus recorded the highest values in the characteristic of an increase in the diameter of the transplants, while the coefficient of 10 ml L^-1 ALGACIFO 3000 recorded a significant increase in the qualities of the leaf area, the number of leaves, the leaves area and the increase in the length and diameter of the transplants.