This study was conducted to evaluate the effectiveness of safe alternative to hydrogen cyanamide in breaking dormancy in Red Roomy' grapevines. The vines were treated with the following spray applications: control, dormex, Erger at a concentration of (3 ,5 %), calcium nitrate at a concentration of   3% and their combinations. The date of spray was carried out at 45 or 30 days before bud opening or in both of prementioned dates. All treatments included dormex, Erger and calcium nitrate and their combinations increased the berry set %. The results also showed improving in the quantity of the yield due to the increasement of the cluster weight and the number of clusters per vines by using the aforesaid treatments. Moreover, using dormex or Erger caused in enhancing cluster dimensions either berry dimensions. in the first season, the higher percentage of T.S.S   and reducing sugars were obtained by vines sprayed either by dormex or by Erger at the highest level combined with calcium nitrate 3%. On contrary the acidity was decreased.